100% Amafutha Emvelo Ahlanzekile Eucommiae Foliuml Abalulekile Okunakekelwa Kwesikhumba

100% Amafutha Emvelo Ahlanzekile Eucommiae Foliuml Amafutha Abalulekile Okunakekelwa Kwesikhumba Isithombe Esifakiwe

incazelo emfushane:

I-Eucommia ulmoides(EU) (evame ukubizwa ngokuthi “Du Zhong” ngolimi lwesiShayina) ingeyomndeni wakwa-Eucommiaceae, uhlobo lwesihlahla esincane esidabuka e-Central China [1]. Lesi sitshalo silinywa kabanzi eShayina ngezinga elikhulu ngenxa yokubaluleka kwaso kwezokwelapha. Cishe izinhlanganisela ze-112 ziye zahlukaniswa ku-EU ezihlanganisa ama-lignans, ama-iridoid, ama-phenolic, ama-steroids, nezinye izinhlanganisela. Ifomula yamakhambi ahambisanayo yalesi sitshalo (njengetiye elimnandi) ibonise izici ezithile zokwelapha. Iqabunga le-EU linomsebenzi ophezulu ohlobene ne-cortex, imbali, nezithelo [2,3]. Kubikwa ukuthi amaqabunga e-EU athuthukisa amandla amathambo nemisipha yomzimba [4], ngaleyo ndlela kuholela ekuphileni isikhathi eside nasekukhuthazeni ukuzala kubantu [5]. Ifomula yetiye elimnandi elenziwe ngeqabunga le-EU kubikwa ukuthi linciphisa ukukhuluphala futhi lithuthukise i-metabolism yamandla. Izithako ze-Flavonoid (ezifana ne-rutin, i-chlorogenic acid, i-ferulic acid, ne-caffeic acid) kubikwe ukuthi zibonisa umsebenzi wama-antioxidants emaqabunga e-EU [6].

Nakuba kube nezincwadi ezanele mayelana nezakhiwo ze-phytochemical ze-EU, zimbalwa izifundo ezikhona mayelana nezakhiwo zekhemisi zezinhlanganisela ezihlukahlukene ezikhishwe kumagxolo, imbewu, iziqu, namaqabunga e-EU. Leli phepha lokubuyekeza lizocacisa ulwazi oluningiliziwe mayelana nenhlanganisela ehlukene ekhishwe ezingxenyeni ezihlukahlukene (amagxolo, imbewu, isiqu, neqabunga) le-EU kanye nokungase kusetshenziswe lezi zinhlanganisela ezindaweni ezikhuthaza impilo ngemigqa yobufakazi besayensi futhi ngaleyo ndlela inikeze izinto ezibhekisela kuzo. ukuze kusetshenziswe i-EU.

Intengo ye-FOB:US $0.5 - 9,999 / Ucezu

Inani elincane le-oda:100 Isiqephu/Izingcezu

Ikhono Lokuhlinzeka:10000 Ucezu/Izingcezu Ngenyanga

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Ama-Lignans kanye nokuphuma kwawo kuyizingxenye ezibalulekile ze-EU [7]. Kuze kube manje, ama-lignans angama-28 (afana nama-bisepoxylignans, monoepoxylignans, neolignans, nama-sesquilignans) ahlukaniswe namagxolo, amaqabunga, kanye nembewu ye-EU. I-Iridoid glycoside, ikilasi lama-metabolites esibili, iyingxenye yesibili eyinhloko ye-EU. Ama-Iridoid ngokuvamile atholakala ezitshalweni ezaziwa ngokuthi ama-glycosides. Ama-iridoid angamashumi amabili nane ahlukanisiwe futhi akhonjwa ku-EU (Ithebula 1). Lezi zinhlanganisela ezihlukanisiwe zihlanganisa i-geniposidic acid, i-aucubin, ne-asperuloside okuye kwabikwa ukuthi inezakhiwo eziningi zemithi [8-10]. Izinhlanganisela ezintsha ezimbili zama-iridoid, i-Eucommides-A kanye no-C, zisanda kuhlukaniswa. Lezi zinhlanganisela ezimbili zemvelo zibhekwa njengama-conjugates e-iridoid nama-amino acid. Nokho, indlela ewumsebenzi wabo ayitholakali [11].

2.2. Ama-Phenolic Compounds

Ama-phenolic compounds atholakala ekudleni kuye kwabikwa ukuthi anomthelela omuhle empilweni yabantu [12,13]. Cishe ama-phenolic compounds angama-29 ahlukanisiwe futhi akhonjwa ku-EU [14]. Ingqikithi yokuqukethwe kwezinhlanganisela ze-phenolic (ngokulingana kwe-gallic acid yazo zonke izingcaphuno) yahlaziywa kusetshenziswa i-Folin-Ciocalteu phenol reagent. Imithelela yokuhlukahluka kwesizini kokuqukethwe kwezinye izinhlanganisela nama-antioxidants kuye kwabikwa. Phakathi nonyaka ofanayo, okuqukethwe okuphezulu kwama-phenolics nama-flavonoid atholakala emaqabunga e-EU ngo-Agasti noMeyi, ngokulandelana. I-Rutin, i-quercetin, i-geniposidic acid, ne-aucubin zazikhona ekugxilweni okuphezulu ngoMeyi noma ngoJuni.15]. Ngaphezu kwalokho, umsebenzi ophezulu we-1,1-diphenyl-2-picrylhydrazyl (DPPH) umsebenzi wokuqothula kakhulu kanye nekhono lokuhlanzwa kwe-ion yensimbi kutholwe emaqabunga e-EU avunwa ngo-Agasti. Ukwenyuka kokuqukethwe kwama-antioxidants okudla nakho kubikwe ngoMeyi uma kuqhathaniswa nezinye izikhathi zonyaka [15]. Iqabunga le-EU litholakale liwumthombo ocebile wama-aminoacids, amavithamini, amaminerali, nama-flavonoid afana ne-quercetin, i-rutin, ne-geniposidic acid [11,16]. Ingqikithi yama-flavonoid ayi-7 ahlukaniswe kuwoI-Eucommiaizitshalo [17]. I-Rutin ne-quercetin yi-flavonoid ebaluleke kakhulu.18]. Ama-Flavonoid ayizinhlanganisela ezibalulekile ezivamile emvelweni futhi zibhekwa njengama-metabolite esibili futhi zisebenza njengezithunywa zamakhemikhali, izilawuli ze-physiological, kanye nama-cell cycle inhibitors.

2.3. Ama-Steroids kanye ne-Terpenoids

Ama-steroid ayisithupha kanye nama-terpenoid amahlanu akhishiwe futhi ahlukaniswa ku-EU. Lezi zihlanganisaβ-sitosterol, daucosterol, ulmoprenol, betalin, betulic acid, ursolic acid, eucommidiol, rehmaglutin C, futhi 1,4α,5,7α-tetrahydro-7-hydroxymethyl-cyclopenta[c]pyran-4-carboxylic methyl ester eyayihlukaniswe ngokukhethekile namagxolo e-EU [19]. I-Loliolide nayo iye yahlukaniswa namaqabunga [20].

2.4. Ama-Polysaccharides

Ama-polysaccharides avela e-EU izinsuku ezingu-15 ekugxilweni kwe-300-600 mg/kg kubikwe ukuthi abonise imiphumela yokuzivikela ezinso njengoba kubonwa amazinga e-malonaldehyde kanye ne-glutathione ngemva kokuchithwa kwezinso [21]. Ukuhlolwa kwe-histological nakho kubonise ubufakazi bezakhiwo ze-antioxidative. Izingcaphuno ezivela egxolweni le-EU zisebenzisa i-ethanol engu-70% nazo zibonise imiphumela yokuzivikela ngokumelene ne-cadmium ku-125-500 mg/kg [22]. Ukuhlolwa kwe-Histological nakho kwabonisa ukuthi i-EU ihlangene neI-Panax pseudoginsengku-25% kanye nesisindo esingu-50%, ngokulandelana, amasonto ayisithupha ngesilinganiso somthamo we-35.7-41.6 mg/kg senze imiphumela yokuvikela ekhanyayo ngesilinganiso sokuhlunga kwe-glomerular [8]. Ama-polysaccharides amabili amasha ahlukaniswe ne-EU, okuyi-eucomman A no-B [23].

2.5. Ezinye Izithako Namakhemikhali

Ama-amino acid, ama-microelements, amavithamini, nama-fatty acids nawo ahlukanisiwe ne-EU [17,21-23]. Ilanga et al. futhi bathole izinhlanganisela ezintsha ezifana ne-n-octacosanoic acid, kanye ne-tetracosanoic-2,3-dihydroxypropylester evela e-EU [24].

Ukwakheka kwe-acid enamafutha akhishwe enzalweni ye-EU kubonise ukugxila okuhlukile kwamafutha e-polyunsaturated afana ne-linoleic acid, i-linolenic acid (amaphesenti angama-56.51 wawo wonke ama-fatty acids, ama-TFAs), kanye ne-linolelaidic acid (12.66% yama-TFAs). Ngaleso sikhathi, i-monounsaturated fatty acid eyinhloko ehlukanisiwe nembewu yatholakala iyi-isoleic acid (15.80% yama-TFAs). Ama-acids agcwele amafutha agcwele ahlukene ahlukanisiwe ahlanganisa i-palmitic acid ne-stearic acid emele u-9.82% no-2.59% wama-TFAs, ngokulandelana.